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Do the chances of remission improve after one year of Braf / mek with no progression and only one lung mass left that has shru by 2/3 to 1.5

A MyMelanomaTeam Member asked a question 💭
White Plains, NY
October 27, 2025
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Does the chance of remission improve after one year on BRAF/MEK inhibitors with no progression and a lung metastasis that has shrunk significantly?

Your situation sounds encouraging! Having no progression after a year on BRAF/MEK inhibitors and seeing your lung metastasis shrink by two-thirds is a positive response to Show Full Answer

Does the chance of remission improve after one year on BRAF/MEK inhibitors with no progression and a lung metastasis that has shrunk significantly?

Your situation sounds encouraging! Having no progression after a year on BRAF/MEK inhibitors and seeing your lung metastasis shrink by two-thirds is a positive response to treatment.

Studies show that BRAF and MEK inhibitors work best when used together in specific combinations, and they can help shrink tumors in people with metastatic melanoma. The fact that your remaining metastasis has responded so well to treatment is a good sign.

However, the available information doesn't provide specific statistics about remission chances based on duration of treatment or degree of tumor shrinkage. Each person's response to these targeted therapies can vary.

What's important is that you're showing a clear treatment response with tumor shrinkage and no progression. Your oncology care team can best evaluate your individual situation and discuss what this means for your specific prognosis and next steps.

Continue working closely with your healthcare team, as they can monitor your progress and adjust your treatment plan as needed.

October 27, 2025
A MyMelanomaTeam Member

Alice,

Per Google's AI overview, and I think this is pretty spot on:

"BRAF is both a gene and a protein that plays a crucial role in regulating cell growth, division, and differentiation. When the BRAF gene has a mutation, it can lead to an abnormal protein that sends signals causing uncontrolled cell growth, which is a hallmark of many cancers, including melanoma, colorectal, and lung cancer. "

I'm responding because I have the BRAF issue as well. And I'm now in remission after four years of starting with surgically removing a brain tumor and a year of immunotherapies.

October 28, 2025

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