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A MyMelanomaTeam Member asked a question 💭
Croatia

It has spread to her lungs and she had immunitherapy for eight or nine months. But it grows every three months and new nodules show up. The dictor stopped the immunotherapy and now she is doing gene testing hoping they will get positive test and give her something appropriate.
The biggest nodules are 24mm(one year ago 9mm) and 17mm.
Does anyone have similar experience

January 8
 · 
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MyMelanomaTeam

What experiences have others had with stage 4 melanoma that has spread to the lungs and continued growing despite immunotherapy?

Your mom's situation with stage 4 melanoma spreading to the lungs is something other members have experienced. When melanoma reaches stage 4, it means it has metastasized to distant organs like Show Full Answer

What experiences have others had with stage 4 melanoma that has spread to the lungs and continued growing despite immunotherapy?

Your mom's situation with stage 4 melanoma spreading to the lungs is something other members have experienced. When melanoma reaches stage 4, it means it has metastasized to distant organs like the lungs, and treatment approaches can vary based on how the cancer responds.

It's encouraging that her doctor is pursuing genetic testing. This is an important step because targeted therapy drugs can be very effective for people whose melanoma cells have specific genetic mutations. These targeted therapies work differently than immunotherapy and may offer better results if the right mutation is found.

When immunotherapy doesn't work as hoped, treatment options can include:
* Targeted therapy (if genetic mutations are found)
* Different immunotherapy combinations
* Chemotherapy (though less commonly used now)
* Clinical trials with newer treatments

The growth you're describing—nodules increasing from 9mm to 24mm and new ones appearing—indicates the melanoma is progressing. This is why switching treatment approaches makes sense. Stage 4 melanoma with lung metastasis can be challenging, but newer treatments like targeted therapies have helped many people live longer. The genetic testing your mom is undergoing could identify mutations that make her eligible for these more personalized treatment options.

Keep communicating openly with her medical team about any new symptoms like fatigue, shortness of breath, or changes in appetite, as these can be important for monitoring her condition and adjusting treatment.

January 8

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