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Treatments have been working very well reducing tumors. For about a month now severe body ache and weakness have developed . Has any one experienced this after over two years of treatment. I can barely tie my shoes

October 18, 2025
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Joint and muscle pain can be a side effect of immunotherapy treatments like Opdivo. This can include muscle aches, joint pain, swelling, and stiffness that make everyday activities difficult. Some people experience these symptoms during treatment, while others may develop them months or even years after starting treatment Show Full Answer

Joint and muscle pain can be a side effect of immunotherapy treatments like Opdivo. This can include muscle aches, joint pain, swelling, and stiffness that make everyday activities difficult. Some people experience these symptoms during treatment, while others may develop them months or even years after starting treatment. Common symptoms that can develop during immunotherapy include:
• Fatigue and weakness
• Body aches
• Fever and chills
• Shortness of breath
• Gastrointestinal issues

Since you're experiencing new or worsening symptoms, it's important to discuss these changes with your cancer care team right away. They can evaluate whether your symptoms are treatment-related and recommend appropriate management strategies.

October 18, 2025

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