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Real members of MyMelanomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyMelanomaTeam Member asked a question 💭
Croatia
January 16
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Are there others with lung metastasis who are BRAF negative?

Yes, many people with melanoma that has spread to the lungs are BRAF negative. Between 70 percent and 87 percent of people with metastatic melanoma experience spread to their lungs, and not all of them have BRAF mutations.

BRAF mutations occur in some melanoma Show Full Answer

Are there others with lung metastasis who are BRAF negative?

Yes, many people with melanoma that has spread to the lungs are BRAF negative. Between 70 percent and 87 percent of people with metastatic melanoma experience spread to their lungs, and not all of them have BRAF mutations.

BRAF mutations occur in some melanoma cases and can affect treatment options, but they're not present in everyone. If you're BRAF negative, your treatment plan will focus on other approaches like immunotherapy rather than BRAF-targeted therapies.

It's worth noting that lung metastasis can occur even many years after the original melanoma diagnosis - sometimes more than 10 years later. Your healthcare team can help determine the best treatment approach based on your specific situation, including whether you have other genetic mutations like NRAS.

You're definitely not alone in this situation, and there are effective treatment options available for BRAF-negative metastatic melanoma.

January 16

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